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We hope that this information will be useful to investigators who are unfamiliar with mouse breeding or who are elegance transgenic or gene targeted mice for the first time. They are unsealed to modification and should not be construed as a comprehensive set of rules. We recommend that transgenic founders or chimeras be mated to C57BL/6 mice. Make a pedigree for each transgenic founder or embryonic stem cell-mouse chimera. Mate mice when they are sexually mature (6 to 8 weeks old). subsequently 6 generations of mating to C57BL/6, added than 99% of the genetic background will be C57BL/6.
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My wife Cathy came home from our son's solar day and announced that she had found out that human calves are born sterile and/or that they official document not breed. Our daughter, then in Veterinary school, came domicile and told us the morning she was leaving for school, to put that heifer in with the calves on feed and sell her, she wouldn't be any good and that you can't verbalize if they're by looking at them if they're normal, lone by pelvic exam. I said that I have always heard that, but do not believe it, as I have ne'er seen scientific proof that it is true. Well, the next salutation the heifer was in heat, we sorted her out, drove her cross-town the barnyard to the heifers that were with a bull. The heifer always looked very feminine and as she was a Registered Angus, we content we would give her a chance, so we didn't put her in the feeder calves.
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